IL5RA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:2000~1:5000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CD125.
Specificity	CD125 polyclonal antibody detects endogenous levels of CD125 protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 60 kDa
Gene Name	interleukin 5 receptor subunit alpha
Database Link	Entrez Gene 3568 Human UniProt ID Q01344
Background	Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils .Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5.In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway .
Synonyms	CD125; CDw125; IL-5 receptor subunit alpha; IL-5R-alpha; IL-5RA; IL-5R subunit alpha; Interleukin-5 receptor subunit alpha
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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