CD32B (FCGR2B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CD32.
Specificity	CD32 (FcgammaRIIb) polyclonal antibody detects endogenous levels of CD32 protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 44 kDa
Gene Name	Fc fragment of IgG receptor IIb
Database Link	Entrez Gene 2213 Human UniProt ID P31994
Background	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Synonyms	CD32; CDw32; Fc-gamma-RIIb; Fc-gamma RII-b; FCG2; FCGR2B; FcRII-b; IGFR2; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-b
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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