Integrin alpha 3 (ITGA3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human Integrin α3 (CD49c).
Specificity	Integrin α3 (CD49c) polyclonal antibody detects endogenous levels of Integrin α3 (CD49c) protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 116 kDa
Gene Name	integrin subunit alpha 3
Database Link	Entrez Gene 3675 Human UniProt ID P26006
Background	Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Synonyms	CD49 antigen-like family member C; CD_antigen: CD49c; FRP-2; Galactoprotein B3; GAPB3; Integrin alpha-3; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; ITGA3; MSK18; VLA-3 subunit alpha
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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