Nox4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Recommended dilution: WB:1:500-1:5000
Reactivity	Rat, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant Rat NADPH oxidase 4 protein (210-424AA)
Isotype	IgG
Formulation	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration	lot specific
Purification	>95%, Protein G purified
Conjugation	Unconjugated
Storage Condition	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Database Link	UniProt ID Q924V1
Background	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Reference Data

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