PSEN2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Recommended dilution: WB:1:500-1:5000
Reactivity	Rat, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant Human Presenilin-2 protein (7-77AA)
Isotype	IgG
Formulation	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Concentration	lot specific
Purification	>95%, Protein G purified
Conjugation	Unconjugated
Storage Condition	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Database Link	UniProt ID P49810
Background	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Reference Data

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