CD37 Rabbit Monoclonal Antibody [Clone ID: MB-1]

Specifications

Product Data
Clone Name	MB-1
Applications	FC, IF, IHC, WB
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma. Immunophenotyping studies of these cells identified them as B cells expressing SIgG/λ, as well as HLA-DR. Leu-12, and B1.
Specificity	This antibody is specific for human CD37, which is expressed on virtually all mature B lymphocytes, but not on pro-B or plasma cells. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 does not appear to be expressed on T cells, thymocytes, granulocytes or platelets. This antibody recognizes human CD37, and has been used to identify and characterise the CD37 antigen in cell labelling, indirect immunofluorescence and IP analysis (Link, 1986). In particular, the use of this antibody to label malignant B cells indicates that expression of CD37 occurs relatively late in B cell maturation, as it is not expressed on "immature" B lineage lymphoid neoplasms.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD37 molecule
Database Link	Entrez Gene 951 Human UniProt ID P11049
Synonyms	GP52-40; MGC120234; tetraspanin-26; Tspan-26; TSPAN26
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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