UBE2I Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, IP, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human UBE2I
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	18kDa
Gene Name	ubiquitin conjugating enzyme E2 I
Database Link	Entrez Gene 7329 Human UniProt ID P63279
Background	Swiss-Prot Acc.P63279.The process of SUMO-1 conjugation is similar to that seen with ubiquitin and other forms of post-translational protein modification. Like ubiquitin, SUMO-1 is conjugated to its target protein by the coordinated action of ubiquitin conjugation enzymes E1, E2 and E3. Ubc9 (or ube2M) is a highly conserved, 158 amino acid protein that acts as a SUMO-1 conjugating enzyme. Ubc9 binds to target proteins through their SUMO-1-CS (consensus sequence) domains and interacts with SUMO via the structurally conserved amino-terminal domain.
Synonyms	C358B7.1; OTTHUMP00000198126; OTTHUMP00000198127; P18; UBC9; UBCE9
Reference Data

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