Prohibitin (PHB) Mouse Monoclonal Antibody [Clone ID: 5H7-D5-E2]

Specifications

Product Data
Clone Name	5H7-D5-E2
Applications	FC, IF, IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/200-1/1000 ICC: 1/200-1/1000 FC: 1/200-1/400
Reactivity	Human, Mouse, Rat, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human PHB expressed in E. Coli.
Isotype	IgG1
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Ascitic Fluid
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	30kDa
Gene Name	prohibitin
Database Link	Entrez Gene 5245 Human UniProt ID P35232
Background	Swiss-Prot Acc.P35232.Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Synonyms	PHB1; prohibitin
Reference Data

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