IKB beta (NFKBIB) Mouse Monoclonal Antibody [Clone ID: 3H3-6E9-9H9]

Specifications

Product Data
Clone Name	3H3-6E9-9H9
Applications	IHC
Recommend Dilution	IHC: 1/100-200
Reactivity	Human, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant protein expressed in E.coli.
Isotype	IgG1
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	48kDa
Gene Name	NFKB inhibitor beta
Database Link	Entrez Gene 4793 Human UniProt ID Q15653
Background	Swiss-Prot Acc.Q15653.Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Synonyms	I-kappa-B-beta; IkappaBbeta; IkB-B; IkB-beta; IKBB; NF-kappa-BIB; TRIP-9; TRIP9
Reference Data

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