KDM4B Rabbit Monoclonal Antibody [Clone ID: R08-9G9]

Specifications

Product Data
Clone Name	R08-9G9
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/1000 IHC: 1/20 ICC/IF: 1/2000
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human KDM4B/JMJD2B
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 122 kDa; Observed MW: 150 kDa
Gene Name	lysine demethylase 4B
Database Link	Entrez Gene 23030 Human UniProt ID O94953
Background	Swiss-Prot Acc.O94953.Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Synonyms	FLJ44906; JHDM3B; JMJD2B; KIAA0876
Reference Data

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