GABARAPL2 Rabbit Monoclonal Antibody [Clone ID: R03-7J2]

Specifications

Product Data
Clone Name	R03-7J2
Applications	WB
Recommend Dilution	WB: 1/1000
Reactivity	Human, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human GABARAPL2
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 14 kDa; Observed MW: 14 kDa
Gene Name	GABA type A receptor associated protein like 2
Database Link	Entrez Gene 11345 Human UniProt ID P60520
Background	Swiss-Prot Acc.P60520.Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 . Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Synonyms	ATG8; FLC3A; GATE-16; GATE16; GEF-2; GEF2
Reference Data

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