Junctional Adhesion Molecule 1 (F11R) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1/500-1/2000 IHC: 1/50-1/200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human JAM1
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	33kDa
Gene Name	F11 receptor
Database Link	Entrez Gene 50848 Human UniProt ID Q9Y624
Background	Swiss-Prot Acc.Q9Y624.Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Synonyms	CD321; JAM; JAM-1; JAM-A; JAM1; JAMA; JCAM; KAT; OTTHUMP00000027880; OTTHUMP00000027881; PAM-1
Reference Data

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