Cytochrome C (CYCS) Rabbit Monoclonal Antibody [Clone ID: R02-9A7]

Specifications

Product Data
Clone Name	R02-9A7
Applications	IF, IP, WB
Recommend Dilution	WB: 1/1000 ICC/IF: 1/20-1/50 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human Cytochrome C
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 12 kDa; Observed MW: 14 kDa
Gene Name	cytochrome c, somatic
Database Link	Entrez Gene 54205 Human UniProt ID P99999
Background	Swiss-Prot Acc.P99999.Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SitesFeature keyPosition(s)Description
Synonyms	CYC; HCS; OTTHUMP00000202043; OTTHUMP00000202044; THC4
Reference Data

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