CIRBP Rabbit Monoclonal Antibody [Clone ID: R01-4B2]

Specifications

Product Data
Clone Name	R01-4B2
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/1000 IHC: 1/200 IP: 1/20
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human CIRBP
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 19 kDa; Observed MW: 19 kDa
Gene Name	cold inducible RNA binding protein
Database Link	Entrez Gene 1153 Human UniProt ID Q14011
Background	Swiss-Prot Acc.Q14011.Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.
Synonyms	A18HNRNP; CIRP
Reference Data

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