N Cadherin (CDH2) Rabbit Monoclonal Antibody [Clone ID: R07-4F1]

Specifications

Product Data
Clone Name	R07-4F1
Applications	IP, WB
Recommend Dilution	WB: 1/1000 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human N Cadherin
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 100 kDa; Observed MW: 140 kDa
Gene Name	cadherin 2
Database Link	Entrez Gene 1000 Human UniProt ID P19022
Background	Swiss-Prot Acc.P19022.Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density .
Synonyms	CD325; CDHN; CDw325; N-cadherin; NCAD
Reference Data

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