Cyclin E2 (CCNE2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommend Dilution	WB: 1/500-1/1000 IHC: 1/50-1/200 ICC/IF: 1/100-1/500 FC: 1/20
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human Cyclin E2
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	47kDa
Gene Name	cyclin E2
Database Link	Entrez Gene 9134 Human UniProt ID O96020
Background	Swiss-Prot Acc.O96020.Cyclin E1 and cyclin E2 can associate with and activate CDK2. Upon DNA damage, upregulatioctivation of the CDK inhibitors p21 Waf1/Cip1 and p27 Kip1 prevent cyclin E/CDK2 activation, resulting in G1/S arrest. Essential for the control of the cell cycle at the late G1 and early S phase.
Synonyms	CYCE2
Reference Data

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