Bcl2 Binding component 3 (BBC3) Rabbit Monoclonal Antibody [Clone ID: R05-9C7]

Specifications

Product Data
Clone Name	R05-9C7
Applications	IF, IHC, WB
Recommend Dilution	WB: 1/1000 IHC: 1/20-1/100 ICC/IF: 1/50-1/100
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human PUMA
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 21 kDa; Observed MW: 21 kDa
Gene Name	BCL2 binding component 3
Database Link	Entrez Gene 27113 Human UniProt ID Q9BXH1
Background	Swiss-Prot Acc.Q9BXH1.Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (PubMed:11463391). Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis (PubMed:23340338).
Synonyms	FLJ42994; JFY-1; JFY1; PUMA
Reference Data

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