Apolipoprotein A I (APOA1) Mouse Monoclonal Antibody [Clone ID: 2D6-3B2-7C2]

Specifications

Product Data
Clone Name	2D6-3B2-7C2
Applications	WB
Recommend Dilution	WB: 1/500-1/2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human APOA1 expressed in E. Coli.
Isotype	IgG1
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Ascitic Fluid
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	25kDa
Gene Name	apolipoprotein A1
Database Link	Entrez Gene 335 Human UniProt ID P02647
Background	Swiss-Prot Acc.P02647.APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Synonyms	Apo-AI; ApoA-I; MGC117399; OTTHUMP00000069346; OTTHUMP00000069347; OTTHUMP00000069348
Reference Data

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