Acid sphingomyelinase (SMPD1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, ICC/IF, WB
Recommend Dilution	WB,1:100 - 1:500 IF/ICC,1:10 - 1:100 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity	Human, Mouse, Rat
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Formulation	Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	70kDa
Gene Name	sphingomyelin phosphodiesterase 1
Database Link	Entrez Gene 6609 Human UniProt ID P17405
Background	The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Synonyms	ASM; aSMase; NPD
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.