pan Kme3 Rabbit Polyclonal Antibody

CAT#: TA379603

pan-Tri-Methyl lysine Rabbit polyclonal Antibody



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CNY 2900.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications ChIP, ELISA, IP, WB
Recommend Dilution WB,1:500 - 1:1000
IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
ChIP,3μg antibody for 5μg-10μg of Chromatin
Reactivity Human, Mouse, Rat, Other (Wide Range)
Modifications pan-tri-Methyl K
Host Rabbit
Clonality Polyclonal
Isotype IgG
Formulation Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 0
Background Methylation of lysine residues is a common regulatory post-translational modification (PTM) that results in the mono-, di-, or tri-methylation of lysine at ε-amine groups by protein lysine methyltransferases (PKMTs).The post-translational ε-amino lysine methylated proteins is an important reversible modification which plays a vital role in the regulation of many cellular processes including chromatin dynamics and gene transcription. Methylation of lysine residues is modulated by specific counteractive enzymes including lysine methylases (KMTs) and demethylases (KDMs). Lysine trimethylation occurs in both histones and non-histone substratres. It has become promising targets for discovery of anti-cancer drugs.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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