MTH1 (NUDT1) Rabbit Polyclonal Antibody

CAT#: TA379394

MTH1 Rabbit polyclonal Antibody

Size: 20 ul 100 ul



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CNY 2900.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications ELISA, IP, WB
Recommend Dilution WB,1:500 - 1:2000
IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human
Modifications Unmodified
Host Rabbit
Clonality Polyclonal
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 18kDa
Gene Name nudix hydrolase 1
Background Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A rare single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.
Synonyms 8-oxo-dGTPase; MTH1; OTTHUMP00000115537; OTTHUMP00000115540
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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