Alpha Dystroglycan (DAG1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, ICC/IF, IP, WB
Recommend Dilution	WB,1:1000 - 1:5000 IF/ICC,1:20 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity	Mouse, Rat, Human
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	97kDa
Gene Name	dystroglycan 1
Database Link	Entrez Gene 1605 Human UniProt ID Q14118
Background	This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
Synonyms	156DAG; A3a; AGRNR; alpha-dystroglycan; beta-dystroglycan; DAG
Reference Data

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