CHURC 1 (CHURC1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CHURC1
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	churchill domain containing 1
Database Link	Entrez Gene 91612 Human UniProt ID Q8WUH1
Background	CHURC1, also known as protein Churchill, is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.
Synonyms	C14orf52; chch; FLJ33064; My015
Reference Data

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