IFITM1 Rabbit Polyclonal Antibody
CAT#: TA371843
IFITM1 rabbit polyclonal antibody
Size: 25 ul
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CNY 1,999.00
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Hela and NIH/3T3 cell IHC: 25-100 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm and Cell membrane |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human IFITM1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 14 kDa |
Gene Name | interferon induced transmembrane protein 1 |
Database Link | |
Background | The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and IFITM3 demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm. |
Synonyms | 9-27; CD225; IFI17; LEU13 |
Reference Data |
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