THNSL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: K562 and 231 cell lysates IHC: 50-300 Positive control: Human esophagus cancer Predicted cell location: Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human THNSL1
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	83 kDa
Gene Name	threonine synthase like 1
Database Link	Entrez Gene 79896 Human UniProt ID Q8IYQ7
Background	THNSL1 (threonine synthase-like 1), also known as TSH1, is a 743 amino acid member of the serine/threonine dehydratase family. Expressed primarily in brain and endocrine glands, THNSL1 is thought to function as a pyridoxal-5'-phosphate (PLP)-dependent enzyme that uses pyridoxal phosphate as a cofactor. THNSL1 shares similarity with bacterial threonine synthases (which synthesize threonine from aspartic acid), suggesting that THNSL1 may have once participated in de novo threonine synthesis within the body, but has since lost its original metabolic role.
Synonyms	FLJ22002; TSH1
Reference Data

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