TTC12 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human bladder transitional cell carcinoma grade 2-3 tissue lysate IHC: 50-300 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human TTC12
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	79 kDa
Gene Name	tetratricopeptide repeat domain 12
Database Link	Entrez Gene 54970 Human UniProt ID Q9H892
Background	TTC12 (tetratricopeptide repeat domain 12), also known as TPARM, is a 705 amino acid cytoplasmic protein containing a TPR repeat domain and three armadillo repeat motifs. TTC12 is expressed in testis, prostate, lung, germinal center B cells, neuroblastoma, teratocarcinoma, colon cancer and gastric cancer. The gene encoding TTC12 is located in a region of human chromosome 11 that is commonly deleted in a variety of cancers, therefore, it is considered a candidate tumor suppressor gene. Human chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome.
Synonyms	FLJ13859; FLJ20535; TPARM
Reference Data

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