MYG1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: PC-3,MCF-7 and 293T cell lysates IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Nucleus and Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human C12orf10
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	42 kDa
Gene Name	chromosome 12 open reading frame 10
Database Link	Entrez Gene 60314 Human UniProt ID Q9HB07
Background	C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility.
Synonyms	MST024; MSTP024; MYG; MYG1
Reference Data

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