SIGLECL1 (SIGLEC12) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse bladder tissue IHC: 25-100 Positive control: Human prostate cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human SIGLEC12
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	65 kDa
Gene Name	sialic acid binding Ig like lectin 12 (gene/pseudogene)
Database Link	Entrez Gene 89858 Human UniProt ID Q96PQ1
Background	Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like.
Synonyms	FLJ38600; S2V; Siglec-12; Siglec-L1; Siglec-XII; SIGLECL1; SLG
Reference Data

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