Cyclin J (CCNJ) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: K562 cell lysate IHC: 10-50 Positive control: Human gastric cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CCNJ
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	43 kDa
Gene Name	cyclin J
Database Link	Entrez Gene 54619 Human UniProt ID Q5T5M9
Background	Cyclin J is a 372 amino acid protein encoded by the human gene CCNJ located on chromosome 10. Cyclin J belongs to the cyclin family and contains one cyclin N-terminal domain. A cyclin forms a complex with its partner cyclin-dependent kinase (Cdk), which activates the protein kinase function of the Cdk. Cyclins are so named because their concentration varies in a cyclical fashion during the cell cycle. They are produced or degraded as needed in order to drive the cell through the different stages of the cell cycle. When its concentrations in the cell are low, the cyclin detaches from the Cdk, inhibiting the activity of the enzyme, probably by causing a protein chain to block the enzymatic site. Cyclin J-associated kinase activity is required for the early embryonic division cycles.
Synonyms	bA690P14.1; FLJ10895
Reference Data

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