IFRD2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 30-150 Positive control: Human lung cancer Predicted cell location: Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human IFRD2
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	interferon-related developmental regulator 2
Database Link	Entrez Gene 7866 Human UniProt ID Q12894
Background	IFRD2 (Interferon-related developmental regulator 2), also known as SKMC15, is a 442 amino acid soluble nuclear protein. IFRD2 is ubiquitously expressed and contains a β-catenin-like repeat, which may indicate an involvement in APC signaling. With 75% homology to IFRD1, IFRD2 may also regulate expression of surface adhesion molecules involved in differentiation and fusion of myogenic satellite cells. Although the gene encoding IFRD2 undergoes overlapping homozygous deletions in many lung cancer cell lines, IFRD2 exhibits no loss-of-function mutations in cancer cells, suggesting a possible role in tumor progression.
Synonyms	FLJ40446; IFNRP; SKMc15; SM15
Reference Data

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