COX7B2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human lymphoma Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human COX7B2
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	cytochrome c oxidase subunit 7B2
Database Link	Entrez Gene 170712 Human UniProt ID Q8TF08
Background	The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.
Synonyms	MGC102754; OTTHUMP00000195111
Reference Data

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