SCYL2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCYL2
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat Homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	102kDa
Gene Name	SCY1 like pseudokinase 2
Database Link	XP_005269075 Entrez Gene 55681 Human UniProt ID Q6P3W7
Background	SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. It may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
Synonyms	CVAK104; FLJ10074; KIAA1360
Reference Data

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