CHMP4A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Human, Rabbit, Rat Homology: Cow: 77%; Human: 100%; Rabbit: 92%; Rat: 85%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	29kDa
Gene Name	charged multivesicular body protein 4A
Database Link	NP_054888 Entrez Gene 29082 Human UniProt ID Q14D22
Background	CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression
Synonyms	C14orf123; CHMP4; CHMP4B; FLJ61658; hSnf-1; HSPC134; hVps32-1; MGC142093; MGC142095; SHAX2; SNF7; SNF7-1; Vps32-1; VPS32A
Reference Data
Protein Pathways	Endocytosis

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