Calpain 3 (CAPN3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat, Sheep Homology: Cow: 79%; Dog: 92%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Rabbit: 86%; Rat: 85%; Sheep: 86%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	93kDa
Gene Name	calpain 3
Database Link	NP_077320 Entrez Gene 825 Human UniProt ID P20807-3
Background	Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Synonyms	CANP3; CANPL3; LGMD2; LGMD2A; MGC4403; MGC10767; MGC11121; MGC14344; nCL-1; NCL1; OTTHUMP00000161194; OTTHUMP00000161196; p94
Reference Data
Protein Families	Druggable Genome, Protease

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