CLN5 Rabbit Polyclonal Antibody

Specifications

Product Data
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human CLN5
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat Homology: Cow: 77%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 86%; Rat: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	39 kDa
Gene Name	ceroid-lipofuscinosis, neuronal 5
Database Link	NP_006484 Entrez Gene 1203 Human UniProt ID O75503
Background	This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Synonyms	FLJ90628; NCL
Reference Data
Protein Pathways	Lysosome

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