LRAT Rabbit Polyclonal Antibody

Specifications

Product Data
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human LRAT
Specificity	Expected reactivity: Human, Pig Homology: Human: 100%; Pig: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	25 kDa
Gene Name	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
Database Link	NP_001288574.1 Entrez Gene 9227 Human UniProt ID O95237
Background	The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.
Synonyms	MGC33103
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Retinol metabolism

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