SFTPA1 Mouse Monoclonal Antibody [Clone ID: 32E12]

Specifications

Product Data
Clone Name	32E12
Applications	IHC
Recommend Dilution	1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to the 104–246 amino acid region of the human prosurfactant A molecule
Specificity	Human surfactant protein A (prosurfactant A)
Isotype	IgG2a
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	surfactant protein A1
Database Link	Entrez Gene 653509 Human UniProt ID Q8IWL2
Background	Pulmonary surfactant plays a critical role in maintaining the structural integrity of the respiratory epithelium by reducing surface tension during expiration. It is a lipoprotein complex which is synthesized and secreted into the alveoli of the lung by type II pneumocytes. Lung surfactant protein-A (SP-A) is a major phospholipid-associated glycoprotein in surfactant and is a member of the C-type lectin superfamily that also inhibits lipid secretion and enhances the uptake of phospholipid by alveolar type II cells. Levels of SP-A in amniotic fluid are reported to reflect the degree of fetal lung maturity and inadequate levels of surfactant at birth, a frequent occurrence in premature infants, results in respiratory failure.
Synonyms	COLEC4; FLJ50593; FLJ51913; FLJ61144; FLJ77898; FLJ79095; FLJ99559; MGC133365; PSAP; PSP-A; PSPA; SFTP1; SFTPA; SP-A; SP-A1
Reference Data

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