IL6 Mouse Monoclonal Antibody [Clone ID: 10C12]

Specifications

Product Data
Clone Name	10C12
Applications	IHC
Recommend Dilution	1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	A prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule
Specificity	Human Interleukin 6
Formulation	Liquid tissue culture supernatant containing 15 mM sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	interleukin 6
Database Link	Entrez Gene 3569 Human UniProt ID P05231
Background	IL-6 is a multifunctional cytokine that is secreted by both lymphoid and non-lymphoid cells. It plays a key role in immune responses, hematopoiesis and is an important cytokine in cell proliferation and differentiation. It may also play an important role as an autocrine growth factor in metastatic prostate cancer. IL-6 has been reported to play a role in secretion or release of pituitary hormone in pituitary hormone secreting cells and adenomas. In addition, IL-6 has been suggested to have a trophic effect in nerve cells and to have a direct pathogenic role in CNS disorders. There are an increasing number of reports that cytokines of the IL-6 family play an important regulatory role in heart physiology.
Synonyms	BSF-2; BSF2; CDF; HGF; HSF; IFNB2; IL-6; OTTHUMP00000158544
Reference Data

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