GCDFP 15 (PIP) Mouse Monoclonal Antibody [Clone ID: 23A3]

Specifications

Product Data
Clone Name	23A3
Applications	IHC
Recommend Dilution	1:40
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant prokaryotic protein corresponding to the excreted domain of the gross cystic disease fluid protein (15 kD) molecule
Specificity	Human gross cystic disease fluid protein (15 kD)
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	prolactin induced protein
Database Link	Entrez Gene 5304 Human UniProt ID P12273
Background	Gross cystic disease of the breast is a benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15 kD monomer protein, GCDFP15. It has been reported that cytosolic analysis of normal tissue from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. Cytosol from breast carcinoma lesions are reported to contain GCDFP15 at a wide range of concentrations. The concentration is reported to be highest in more differentiated carcinomas and GCDFP15 shows only a few positive individual epithelial cells within lobules and small ducts in normal breast. Expression has also been reported in fibroadenomas within areas of apocrine metaplasia.
Synonyms	GCDFP-15; GCDFP15; gp17; GPIP4; SABP
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.