S Protein Rabbit Monoclonal Antibody [Clone ID: DM35]

Specifications

Product Data
Clone Name	DM35
Applications	ELISA, FC
Recommend Dilution	Flow Cyt  1/100
Reactivity	SARS-CoV-2
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD (Arg319-Phe541)(TP724025) produced by using human HEK293 cells
Isotype	IgG
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Preservative: 0.1% Procline 300
Reconstitution Method	Reconstitute with deionized water
Purification	Purified from cell culture supernatant by affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Predicted Protein Size	141kDa
Gene Name	S Protein
Database Link	Entrez Gene 43740568 SARS-CoV-2
Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.
Reference Data

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