BCL2L2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat, Chicken, Bovine, Canis
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide derived from N-terminus of human BCL-W protein. This sequence is identical among human, rat and mouse origins.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21 kDa
Gene Name	BCL2 like 2
Database Link	NP_001186768 Entrez Gene 12050 MouseEntrez Gene 60434 RatEntrez Gene 599 Human UniProt ID Q92843
Background	BCL-w is a member of the Bcl-2 family. The gene codes for a 21 kDa protein which is essential for the regulation of cellular survival, and that is up-regulated in different human tumors, such as gastric and colorectal carcinomas. Inhibition of AKT activity may promote apoptosis through the down-regulation of Bcl-w protein and the consequential reduction in interaction of Bcl-w with pro-apoptotic members of the Bcl-2 family.
Synonyms	BCL-W; BCL2-L-2; BCLW; PPP1R51
Reference Data
Protein Families	Druggable Genome, Transmembrane

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