ORP150 (HYOU1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide next to the C-terminus of HYOU1 protein. This sequence is identical to rat, mouse, human and dog, bovine and horse origins.
Isotype	IgG
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~150 kDa
Gene Name	hypoxia up-regulated 1
Database Link	NP_001124463 Entrez Gene 12282 MouseEntrez Gene 192235 RatEntrez Gene 10525 Human UniProt ID Q9Y4L1
Background	The Hypoxia up-regulated 1 (HYOU1) protein belongs to the heat shock protein 70 family. It plays an important role in protein folding and secretion in the endoplasmic reticulum (ER). This protein is involved in stress-dependent induction, resulting in the accumulation of this protein in the ER under hypoxic conditions. It also has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness.
Synonyms	GRP-170; Grp170; HSP12A; ORP-150; ORP150
Reference Data
Protein Families	Transmembrane

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