Insulin Receptor (INSR) Mouse Monoclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Highly purified human placental Insulin Receptor.
Isotype	IgG1
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~135 kDa
Gene Name	insulin receptor
Database Link	NP_000199 Entrez Gene 3643 Human UniProt ID P06213
Background	The human insulin receptor is a heterotetrametric membrane glycoprotein consisting of disulfide-linked subunits in a β-a-a-β Configuration. The beta-subunit (95kDa) possesses a single transmembrane domain, whereas the alpha subunit (135kDa) is completely extracellular.
Synonyms	CD220; HHF5
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Adherens junction, Insulin signaling pathway, Type II diabetes mellitus

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.