CD147 (BSG) Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	WB 0.1-1 µg/ml ELISA N/A IP N/A IHC 2-10 µg/ml FC Not tested
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of full length of human CD147.
Isotype	IgG
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	27 kDa
Gene Name	basigin (Ok blood group)
Database Link	NP_001309172 Entrez Gene 682 Human UniProt ID P35613
Background	CD147 or EMMPRIN (extracellular matrix metalloproteinase inducer) is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. This protein is also a member of the immunoglobulin super-family, it is a 58kDa protein with two immunoglobulin domains that was originally purified from the plasma membrane of the human LX-1 lung carcinoma cell line. CD147 has been localized on the outer surface of tumor cells, where it interacts withfibroblasts to stimulate the expression of matrix metalloproteinases (MMPs). CD147 inhibition has been proposed as a novel strategy in the prevention of cancer invasion and metastasis.
Synonyms	5F7; CD147; EMMPRIN; OK; TCSF
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.