TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: B-C7]

Specifications

Product Data
Clone Name	B-C7
Recommend Dilution	ELISA, Intracellular staining, Immunohistochemistry, Neutralization assay
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	TNF-alpha
Formulation	Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
Concentration	lot specific
Purification	Ion exchange chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.5 kDa
Gene Name	tumor necrosis factor
Database Link	NP_000585 Entrez Gene 7124 Human UniProt ID P01375
Background	The monoclonal antibody to human TNF-alpha (clone B-C7) has shown to be suitable for intracellular staining (Birebent B. et al. 1998) and neutralization assays (Hamacher J. et al. 2002 and van Hensbroek M.B. et al. 1996). B-C7 antibody recognizes both natural and recombinant human TNF-alpha and can be used in ELISA (Robinet E. et al. 1997) and immunohistochemistry (Voorzanger N. et al. 1996).
Synonyms	DIF; TNF-alpha; TNFA; TNFSF2
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane
Protein Pathways	Adipocytokine signaling pathway, Allograft rejection, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Asthma, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Fc epsilon RI signaling pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Natural killer cell mediated cytotoxicity, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus, Type II diabetes mellitus

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.