CLDND2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela, 293T, PC3 and TM4 cell IHC: 30-150 Positive control: Human breast cancer Predicted cell location: Cytoplasm and Cell membrane
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CLDND2
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	claudin domain containing 2
Database Link	NP_689566 Entrez Gene 125875 Human UniProt ID Q8NHS1
Background	CLDND2 (claudin domain containing 2) is a 167 amino acid multi-pass membrane protein that belongs to the PMP-22/EMP/MP20 family and is encoded by a gene that maps to human chromosome 19q13.33. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
Synonyms	MGC33839
Reference Data
Protein Families	Transmembrane

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