NME2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Hela, NIH/3T3, LNCap and 293T cells, Mouse brain tissue, A549 and Jurkat cells IHC: 30-150 Positive control: Human prostate cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human NME2
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	17 kDa
Gene Name	NME/NM23 nucleoside diphosphate kinase 2
Database Link	NP_002503 Entrez Gene 18103 MouseEntrez Gene 83782 RatEntrez Gene 4831 Human UniProt ID P22392
Background	Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.
Synonyms	NDKB; NDPK-B; NDPKB; NM23-H2; NM23B; PUF
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Metabolic pathways, Purine metabolism, Pyrimidine metabolism

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