PP1C gamma (PPP1CC) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Jurkat, 293T and hela cells, mouse brain tissue and K562 cells IHC: 100-300 Positive control: Human lung cancer Predicted cell location: Cytoplasm or Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PPP1CC
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37 kDa
Gene Name	protein phosphatase 1 catalytic subunit gamma
Database Link	NP_002701 Entrez Gene 19047 MouseEntrez Gene 24669 RatEntrez Gene 5501 Human UniProt ID P36873
Background	The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	PP-1G; PP1C; PPP1G
Reference Data
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Focal adhesion, Insulin signaling pathway, Long-term potentiation, Oocyte meiosis, Regulation of actin cytoskeleton, Vascular smooth muscle contraction

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