MARK1 Rabbit Polyclonal Antibody
CAT＃: TA351383S
Rabbit Polyclonal Anti-MARK1 Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: K562 cells IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm and Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MARK1 |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 89 kDa |
| Gene Name | microtubule affinity regulating kinase 1 |
| Database Link | |
| Background | MARK1 is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart. |
| Synonyms | MARK; Par-1c; Par1c |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
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Resources
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