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IL19 Rabbit Polyclonal Antibody
CAT＃: TA351285S
Rabbit Polyclonal Anti-IL19 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Raji, Hela and Jurkat cell lysates IHC: 50-100 Positive control: Human colorectal cancer Predicted cell location: Secreted |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IL19 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 20 kDa |
| Gene Name | interleukin 19 |
| Database Link | |
| Background | The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. |
| Synonyms | IL-10C; MDA1; NG.1; ZMDA1 |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
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